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HOXA13 Antibody - middle region : FITC (ARP31955_P050-FITC)

100 ul
$289.00
In Stock
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Conjugation Options

ARP31955_P050 Unconjugated

ARP31955_P050-HRP Conjugated

ARP31955_P050-Biotin Conjugated

Gene Symbol:
HOXA13
Official Gene Full Name:
Homeobox A13
NCBI Gene Id:
3209
Protein Name:
Homeobox protein Hox-A13
Swissprot Id:
P31271
Protein Accession #:
NP_000513
Nucleotide Accession #:
NM_000522
Alias Symbols:
HOX1, HOX1J
Replacement Item:
This antibody may replace item sc-133669 from Santa Cruz Biotechnology.
Description of Target:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
Protein Size (# AA):
388
Molecular Weight:
40kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HOXA13.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HOXA13.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA13
Predicted Species Reactivity:
Dog, Human, Mouse
Predicted Homology Based on Immunogen Sequence:
Dog: 83%; Human: 100%; Mouse: 92%
Complete computational species homology data:
Anti-HOXA13 (ARP31955_P050)
Peptide Sequence:
Synthetic peptide located within the following region: AAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAA
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
1 mg/ml
Protein Interactions:
UBC; MEIS3; SMAD5; MEIS2; MEIS1; SMAD1; SMAD2;
Blocking Peptide:
For anti-HOXA13 (ARP31955_P050-FITC) antibody is Catalog # AAPY04304
Datasheets/Manuals:
Printable datasheet for anti-HOXA13 (ARP31955_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm
Publications:

Villavicencio-Lorini, P. et al. Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J. Clin. Invest. 120, 1994-2004 (2010). WB, IHC, Human, Mouse, Dog 20458143

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