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HOXA13 antibody - middle region (ARP31955_P050)

100 ul
$289.00
In Stock

Conjugation Options

ARP31955_P050-FITC Conjugated

ARP31955_P050-HRP Conjugated

ARP31955_P050-Biotin Conjugated

Gene Symbol:
HOXA13
NCBI Gene Id:
3209
Official Gene Full Name:
Homeobox A13
Protein Name:
Homeobox protein Hox-A13
Swissprot Id:
P31271
Protein Accession #:
NP_000513
Nucleotide Accession #:
NM_000522
Alias Symbols:
HOX1, HOX1J
Replacement Item:
This antibody may replace item sc-133669 from Santa Cruz Biotechnology.
Description of Target:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
Protein Size (# AA):
388
Molecular Weight:
40kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HOXA13.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HOXA13.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA13
Species Reactivity:
Dog, Human, Mouse
Predicted Homology Based on Immunogen Sequence:
Dog: 83%; Human: 100%; Mouse: 92%
Complete computational species homology data:
Anti-HOXA13 (ARP31955_P050)
Peptide Sequence:
Synthetic peptide located within the following region: AAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAA
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; MEIS3; SMAD5; MEIS2; MEIS1; SMAD1; SMAD2;
Blocking Peptide:
For anti-HOXA13 (ARP31955_P050) antibody is Catalog # AAPY04304
Datasheets/Manuals:
Printable datasheet for anti-HOXA13 (ARP31955_P050) antibody
Publications:

Villavicencio-Lorini, P. et al. Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J. Clin. Invest. 120, 1994-2004 (2010). WB, Dog, Human, Mouse 20458143

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