Size:100 ul
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ARP40620_P050
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Conjugation Options

ARP40620_P050-FITC Conjugated

ARP40620_P050-HRP Conjugated

ARP40620_P050-Biotin Conjugated

HNRPM Antibody - N-terminal region (ARP40620_P050)

Catalog#: ARP40620_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-134360 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPM
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 93%; Rat: 93%
Complete computational species homology data Anti-HNRPM (ARP40620_P050)
Peptide Sequence Synthetic peptide located within the following region: ATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFE
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-HNRNPM (ARP40620_P050) antibody is Catalog # AAP40620 (Previous Catalog # AAPP22380)
Datasheets/Manuals Printable datasheet for anti-HNRNPM (ARP40620_P050) antibody
Sample Type Confirmation

HNRNPM is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Target Reference Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)
Publications

Huelga, S. C. et al. Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins. Cell Rep. 1, 167-78 (2012). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat 22574288

Gene Symbol HNRNPM
Official Gene Full Name Heterogeneous nuclear ribonucleoprotein M
Alias Symbols DKFZp547H118, HNRNPM, HNRNPM4, HNRPM4, HTGR1, NAGR1, CEAR, HNRPM, hnRNP M
NCBI Gene Id 4670
Protein Name Heterogeneous nuclear ribonucleoprotein M
Description of Target HNRPM belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPM has three repeats of quasi-RRM domains that bind to RNAs. HNRPM also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.
Swissprot Id P52272
Protein Accession # NP_112480
Nucleotide Accession # NM_031203
Protein Size (# AA) 691
Molecular Weight 73kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express HNRPM.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express HNRPM.
Protein Interactions UBC; TP53; AKAP9; TEKT4; GMCL1P1; LMO2; HNRNPF; SUMO2; SUMO3; CEP250; MDM2; HAUS1; CDC37; IVNS1ABP; STAU1; SUMO1; RPA3; RPA2; RPA1; EED; rev; RTCB; RPL26L1; RFC4; PSMB8; NMT1; MRE11A; FLII; IGF2BP3; EIF2B2; EIF2B3; RPL27; RPL19; DHX9; DDX1; ABCF1; PARK2;
  1. What is the species homology for "HNRPM Antibody - N-terminal region (ARP40620_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat".

  2. How long will it take to receive "HNRPM Antibody - N-terminal region (ARP40620_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HNRPM Antibody - N-terminal region (ARP40620_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HNRPM Antibody - N-terminal region (ARP40620_P050)"?

    This target may also be called "DKFZp547H118, HNRNPM, HNRNPM4, HNRPM4, HTGR1, NAGR1, CEAR, HNRPM, hnRNP M" in publications.

  5. What is the shipping cost for "HNRPM Antibody - N-terminal region (ARP40620_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HNRPM Antibody - N-terminal region (ARP40620_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HNRPM Antibody - N-terminal region (ARP40620_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "73kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HNRPM Antibody - N-terminal region (ARP40620_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "HNRNPM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HNRNPM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HNRNPM"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HNRNPM"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HNRNPM"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HNRNPM"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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