Catalog No: ARP40240_T100
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ARP40240_T100
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Datasheets/ManualsPrintable datasheet for anti-HNRNPL (ARP40240_T100) antibody
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human HNRPL
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 83%
Peptide SequenceSynthetic peptide located within the following region: DTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHD
Concentration1.0 mg/ml
Blocking PeptideFor anti-HNRNPL (ARP40240_T100) antibody is Catalog # AAP40240 (Previous Catalog # AAPP22084)
Sample Type Confirmation

There is BioGPS gene expression data showing that HNRNPL is expressed in HepG2

ReferenceGuang,S., (2005) Mol. Cell. Biol. 25 (15), 6303-6313
Gene SymbolHNRNPL
Gene Full NameHeterogeneous nuclear ribonucleoprotein L
Alias SymbolsHNRPL, hnRNP-L, P/OKcl.14
NCBI Gene Id3191
Protein NameHeterogeneous nuclear ribonucleoprotein L
Description of TargetHeterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
Uniprot IDP14866
Protein Accession #NP_001524
Nucleotide Accession #NM_001533
Protein Size (# AA)589
Molecular Weight65kDa
Protein InteractionsTP53; FUS; TRIM68; SUMO2; SUMO3; IVNS1ABP; UBC; MDM2; RPA3; RPA2; RPA1; ILF3; HNRNPA2B1; EED; VHL; VEGFA; RNF2; NEDD4; ITCH; FBXO6; HMGA1; vif; TP63; UBL4A; WHSC1; VCAM1; ITGA4; IL7R; IFIT3; IFIT2; FN1; DAB2; CSNK2A1; EIF4A3; MAGOH; HNRNPA3; NPLOC4; LSM14
  1. What is the species homology for "HNRPL Antibody - N-terminal region (ARP40240_T100)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "HNRPL Antibody - N-terminal region (ARP40240_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HNRPL Antibody - N-terminal region (ARP40240_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HNRPL Antibody - N-terminal region (ARP40240_T100)"?

    This target may also be called "HNRPL, hnRNP-L, P/OKcl.14" in publications.

  5. What is the shipping cost for "HNRPL Antibody - N-terminal region (ARP40240_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HNRPL Antibody - N-terminal region (ARP40240_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HNRPL Antibody - N-terminal region (ARP40240_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "65kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HNRPL Antibody - N-terminal region (ARP40240_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HNRNPL"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HNRNPL"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HNRNPL"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HNRNPL"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HNRNPL"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HNRNPL"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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