Size:100 ul
Special Price $229.00 Regular Price $289.00
In Stock
SKU
ARP38532_P050
Request Bulk
Order Quote
Aviva's
Satisfaction
Guarantee
Contact Us:
  • Toll Free: (888)880-0001
  • Phone: (858)552-6979
  • Email: info@avivasysbio.com
Shipping Info:
  • $40: Antibody & Protein in US
  • $50: 1-2 Kits in US
  • Contact us for international orders.

Conjugation Options

ARP38532_P050-FITC Conjugated

ARP38532_P050-HRP Conjugated

ARP38532_P050-Biotin Conjugated

HMGN1 Antibody - middle region (ARP38532_P050)

Catalog#: ARP38532_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-19074 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human HMGN1
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 93%; Rat: 79%
Complete computational species homology data Anti-HMGN1 (ARP38532_P050)
Peptide Sequence Synthetic peptide located within the following region: QTKGKRGAKGKQAEVANQETKEDLPAENGETKTEESPASDEAGEKEAKSD
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-HMGN1 (ARP38532_P050) antibody is Catalog # AAP38532 (Previous Catalog # AAPP20723)
Datasheets/Manuals Printable datasheet for anti-HMGN1 (ARP38532_P050) antibody
Target Reference Zhu,N. (2007) Mol. Cell. Biol. 27 (24), 8859-8873
Publications

Lane, A. A. et al. Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. Nat. Genet. 46, 618-23 (2014). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat 24747640

Gene Symbol HMGN1
Official Gene Full Name High mobility group nucleosome binding domain 1
Alias Symbols FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425
NCBI Gene Id 3150
Protein Name High-mobility group nucleosome binding domain 1 EMBL AAH70154.1
Description of Target Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot Id Q6NSG7
Protein Accession # NP_004956
Nucleotide Accession # NM_004965
Protein Size (# AA) 100
Molecular Weight 11kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express HMGN1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express HMGN1.
Protein Interactions UBC; RPS6KA3; PRKCA; PRKACG; SLC38A3; PPP1CC; LIG4; PPIP5K1; TERF2; SPP1; POLR2A; ERCC8; HDGF; EP300; BTG2; ERCC6; NFE2; RPS6KA5; RPS6KA4; PRKACA; YWHAZ; HMGN1; HMGN2; IRF2;
  1. What is the species homology for "HMGN1 Antibody - middle region (ARP38532_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat".

  2. How long will it take to receive "HMGN1 Antibody - middle region (ARP38532_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HMGN1 Antibody - middle region (ARP38532_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HMGN1 Antibody - middle region (ARP38532_P050)"?

    This target may also be called "FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425" in publications.

  5. What is the shipping cost for "HMGN1 Antibody - middle region (ARP38532_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HMGN1 Antibody - middle region (ARP38532_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HMGN1 Antibody - middle region (ARP38532_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "11kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HMGN1 Antibody - middle region (ARP38532_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "HMGN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HMGN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HMGN1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HMGN1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HMGN1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HMGN1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:HMGN1 Antibody - middle region (ARP38532_P050)
Your Rating
We found other products you might like!