Size:100 ul
Special Price $229.00 Regular Price $249.00
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ARP41562_T100
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Conjugation Options

ARP41562_T100-FITC Conjugated

ARP41562_T100-HRP Conjugated

ARP41562_T100-Biotin Conjugated

HMGCS2 Antibody - N-terminal region (ARP41562_T100)

Catalog#: ARP41562_T100
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-121641 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HMGCS2
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data Anti-HMGCS2 (ARP41562_T100)
Peptide Sequence Synthetic peptide located within the following region: PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQE
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-HMGCS2 (ARP41562_T100) antibody is Catalog # AAP41562 (Previous Catalog # AAPP24247)
Datasheets/Manuals Printable datasheet for anti-HMGCS2 (ARP41562_T100) antibody
Target Reference Bouchard,L., (2001) Pediatr. Res. 49 (3), 326-331
Publications

Clara, R; Schumacher, M; Ramachandran, D; Fedele, S; Krieger, JP; Langhans, W; Mansouri, A; Metabolic Adaptation of the Small Intestine to Short- and Medium-Term High-Fat Diet Exposure. 232, 167-75 (2017). WB, Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 27061934

Karimian Azari, E., Leitner, C., Jaggi, T., Langhans, W. & Mansouri, A. Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-alpha agonist Wy-14643 in high-fat diet fed rats. PLoS One 8, e74869 (2013). WB, Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 24069361

Gene Symbol HMGCS2
Official Gene Full Name 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
NCBI Gene Id 3158
Protein Name Hydroxymethylglutaryl-CoA synthase, mitochondrial
Description of Target HMGCS2 condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Swissprot Id P54868
Protein Accession # NP_005509
Nucleotide Accession # NM_005518
Protein Size (# AA) 508
Molecular Weight 56kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express HMGCS2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express HMGCS2.
Protein Interactions UBC; APP; YWHAQ;
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