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HMGCS2 Antibody - C-terminal region (OAAB03887)

400ul
$390.00
In Stock
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Gene Symbol:
HMGCS2
NCBI Gene Id:
3158
Protein Name:
Hydroxymethylglutaryl-CoA synthase, mitochondrial
Swissprot Id:
P54868
Protein Accession #:
NP_001159579.1
Alias Symbols:
Hydroxymethylglutaryl-CoA synthase, mitochondrial, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, HMGCS2
Replacement Item:
This antibody may replace item sc-121641 from Santa Cruz Biotechnology.
Molecular Weight:
56635 Da
Host:
Rabbit
Clonality:
Polyclonal
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Application:
WB, IHC, FC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HMGCS2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HMGCS2.
Immunogen:
This HMGCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-508 amino acids from the C-terminal region of human HMGCS2.
Predicted Species Reactivity:
Human, Rat
Predicted Homology Based on Immunogen Sequence:
Human; Rat
Product Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for anti-HMGCS2 antibody - OAAB03887
Isotype:
Rabbit Ig
Application Info:
WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
Additional Information:
Function: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
:::
Cellular Location: Mitochondrion.
Tissue Location: Expression in liver is 200-fold higher than in any other tissue. Low expression in colon, kidney, testis, and pancreas. Very low expression in heart and skeletal muscle. Not detected in brain. The relative expression of isoform 3 (at mRNA level) is highest in heart (70%) and skeletal muscle (60%)

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