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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

HMGA2 antibody - N-terminal region (ARP38356_T100)

100 ul
$229.00
In Stock

Conjugation Options

ARP38356_T100-FITC Conjugated

ARP38356_T100-HRP Conjugated

ARP38356_T100-Biotin Conjugated

Gene Symbol:
HMGA2
NCBI Gene Id:
8091
Official Gene Full Name:
High mobility group AT-hook 2
Protein Name:
High mobility group protein HMGI-C
Swissprot Id:
P52926
Protein Accession #:
NP_003474
Nucleotide Accession #:
NM_003483
Alias Symbols:
BABL, HMGI-C, HMGIC, LIPO, STQTL9
Replacement Item:
This antibody may replace item sc-130024 from Santa Cruz Biotechnology.
Description of Target:
HMGA2 belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. It may be play a role in adipogenesis, mesenchymal differentiation and diet-induced obesity.This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Protein Size (# AA):
109
Molecular Weight:
12kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HMGA2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HMGA2.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA2
Species Reactivity:
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 100%
Complete computational species homology data:
Anti-HMGA2 (ARP38356_T100)
Peptide Sequence:
Synthetic peptide located within the following region: PSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
PSIP1; SYNCRIP; PTBP1; PCBP2; PA2G4; NPM1; XRCC6; APEX1; HDGF; UBC; PRKCA; SMAD9; SMAD5; SMAD1; PRMT6; RB1; PIAS3; SMAD3; RELA; NFKB1; CDK1; CSNK2A2; CSNK2A1;
Blocking Peptide:
For anti-HMGA2 (ARP38356_T100) antibody is Catalog # AAP38356 (Previous Catalog # AAPP20543)
Datasheets/Manuals:
Printable datasheet for anti-HMGA2 (ARP38356_T100) antibody
Sample Type Confirmation:

HMGA2 is supported by BioGPS gene expression data to be expressed in HEK293T

Target Reference:
Kubo,T., (2006) Biochem. Biophys. Res. Commun. 340 (2), 476-481

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