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Datasheets/Manuals | Printable datasheet for HLA-G Antibody (OAEE00439) (OAEE00439) |
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Predicted Species Reactivity | Human |
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Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Clonality | Monoclonal |
Clone | MEM-G/2 |
Isotype | IgG1 |
Host | Mouse |
Application | Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | 2°C to 8°C |
Immunogen | Bacterially expressed recombinant HLA-G heavy chain (denatured). |
Purification | Purified |
Concentration | 1 mg/ml |
Specificity | The antibody MEM-G/2 recognizes the free heavy chain of all the HLA-G isoforms. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells. |
Application Info | WB: 1-2 ug/mL |
Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
Reference | Le Discorde M, Moreau P, Sabatier P, Legeais JM, Carosella ED: Expression of HLA-G in human cornea, an immune-privileged tissue. Hum Immunol. 2003 Nov;64(11):1039-44. Poláková K, Bandzuchová E, Hofmeister V, Weiss EH, Hutter H, Russ G: Binding analysis of HLA-G specific antibodies to hematopoietic cells isolated from leukemia patients. Neoplasma. 2003;50(5):331-8. Lazana I, Zoudiari A, Kokkinou D, Themeli M, Liga M, Papadaki H, Papachristou D, Spyridonidis A: Identification of a novel HLA-G+ regulatory population in blood: expansion after allogeneic transplantation and de novo HLA-G expression at graft-versus-host disease sites. Haematologica. 2012 Sep;97(9):1338-47 Boyson JE, Erskine R, Whitman MC, Chiu M, Lau JM, Koopman LA, Valter MM, Angelisova P, Horejsi V, Strominger JL: Disulfide bond-mediated dimerization of HLA-G on the cell surface. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16180-5. Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, LeDanff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 64(3):315-26. Creput C, Durrbach A, Menier C, Guettier C, Samuel D, Dausset J, Charpentier B, Carosella ED, Rouas-Freiss N. Human leukocyte antigen-G (HLA-G) expression in biliary epithelial cells is associated with allograft acceptance in liver-kidney transplantation. J Hepatol. 2003 39(4):587-94. |
Gene Symbol | HLA-G |
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Gene Full Name | major histocompatibility complex, class I, G |
Alias Symbols | b2 microglobulin;HLA class I histocompatibility antigen, alpha chain G;HLA G antigen;HLA-G histocompatibility antigen, class I, G;MHC class I antigen G;MHC class Ib antigen;MHC-G;mutant MHC class I antigen;mutant MHC class Ib antigen. |
NCBI Gene Id | 3135 |
Protein Name | HLA class I histocompatibility antigen, alpha chain G |
Description of Target | Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells. |
Uniprot ID | P17693 |
Protein Accession # | NP_002118.1 |
Nucleotide Accession # | NM_002127.5 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "HLA-G Antibody (OAEE00439)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "HLA-G Antibody (OAEE00439)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "HLA-G Antibody (OAEE00439)" provided in?
This item is provided in "Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "HLA-G Antibody (OAEE00439)"?
This target may also be called "b2 microglobulin;HLA class I histocompatibility antigen, alpha chain G;HLA G antigen;HLA-G histocompatibility antigen, class I, G;MHC class I antigen G;MHC class Ib antigen;MHC-G;mutant MHC class I antigen;mutant MHC class Ib antigen." in publications.
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What is the shipping cost for "HLA-G Antibody (OAEE00439)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "HLA-G Antibody (OAEE00439)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "HLA-G Antibody (OAEE00439)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "HLA-G Antibody (OAEE00439)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "HLA-G"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "HLA-G"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "HLA-G"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "HLA-G"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "HLA-G"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "HLA-G"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.