Catalog No: OATA00455
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SKU
OATA00455
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Datasheets/ManualsPrintable datasheet for OATA00455
Product Info
Tested Species ReactivityHuman
Product FormatLiquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2
ClonalityMonoclonal
CloneLN3
IsotypeMouse IgG2b, kappa
HostMouse
ConjugationPE: Phycoerythrin, CY7: Cyanine 7
ApplicationFC
::Excitation Laser: Blue (488 nm), Green (532 nm), Yellow-Green (561 nm)
::Emmision: 785 nm
Reconstitution and Storage2-8C protected from light
SpecificityHLA-DR
Application InfoThis antibody preparation has been pre-titrated and quality-tested for flow cytometry using an appropriate cell type. The antibody has been diluted for use at 5 uL per test, defined as the amount of antibody that will stain a cell sample in a final volume of approximately 100 uL. The number of cells within a sample should be determined empirically, but typically ranges between 1x10e5 to 1x10e8 cells.
Reference

Eckert F, Schmid U. 1989. Arch Dermatol. 125(11):1518-1524.

Swanson PE, Wick MR. 1990. Mod Pathol. 3(2):113-119.

Shin SS, Sheibani K, Kezirian J, Nademanee A, Forman SJ, Lee SK, Winberg CD. 1992. Hum Pathol. 23(6):686-694.

Sugita S, Iwasaki Y, Makabe K, Kimura T, Futagami T, Suegami S, Takahashi M. 2016. Stem Cell Reports. 11;7(4):619-634.

Gene SymbolHLA-DRA
Gene Full Namemajor histocompatibility complex, class II, DR alpha
Alias SymbolsHLA-DRA1
NCBI Gene Id3122
Protein NameHLA class II histocompatibility antigen, DR alpha chain
Description of TargetHLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Uniprot IDP01903
Protein Accession #NP_061984.2
Nucleotide Accession #NM_019111.4
  1. What is the species homology for "HLA-DRA Antibody : PE-Cy7 (OATA00455)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "".

  2. How long will it take to receive "HLA-DRA Antibody : PE-Cy7 (OATA00455)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "HLA-DRA Antibody : PE-Cy7 (OATA00455)" provided in?

    This item is provided in "Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HLA-DRA Antibody : PE-Cy7 (OATA00455)"?

    This target may also be called "HLA-DRA1" in publications.

  5. What is the shipping cost for "HLA-DRA Antibody : PE-Cy7 (OATA00455)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HLA-DRA Antibody : PE-Cy7 (OATA00455)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HLA-DRA Antibody : PE-Cy7 (OATA00455)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HLA-DRA Antibody : PE-Cy7 (OATA00455)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HLA-DRA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HLA-DRA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HLA-DRA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HLA-DRA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HLA-DRA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HLA-DRA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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