Catalog No: OPPA01533 (Formerly GWB-19614F)
Size:100UG
Price: $192.00
SKU
OPPA01533
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HIV-1 Integrase p31 Protein (OPPA01533)

Datasheets/ManualsPrintable datasheet for OPPA01533
Product Info
Predicted Species ReactivityHuman Immunodeficiency Virus Type 1
Product FormatLiquid 1.5M urea, 25mM Tris-HCl (pH 8.0), 0.2% Triton-X and 50% glycerol
HostE. Coli
ApplicationELISA, WB
Reconstitution and StorageHIV-1 Integrase p31 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Concentration1 mg/ml
PurityGreater than 95.0% as determined by HPLC analysis and SDS-PAGE.
SpecificityImmunoreactive with all sera of HIV-1 infected individuals.
Application InfoHIV-1 Integrase p31 antigen is suitable for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
Gene SymbolHIV-1 Integrase
Alias SymbolsHIV-1 Integrase p31, HIV-1 Integrase p31 Recombinant
Description of TargetIntegrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization, a central catalytic domain and a C-terminal domain. Both Central catalytic domain and C-terminal domains have been shown to bind both viral and cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally, several host cellular proteins interact with integrase and may facilitate the integration process. The E.coli derived recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the p31 protein (integrase) 9-289 amino acids, fused with six histidines at N-terminus.
Protein Size (# AA)Recombinant
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