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Histone H3 Antibody (Tri-Methyl-Lys9) (OADC00278)

50ug
$439.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Monoclonal
Host:
Fab format with human framework
Conjugation:
Unconjugated
Application:
CHIP, IF
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-105519 from Santa Cruz Biotechnology.
Purification:
Affinity purified
Predicted Homology Based on Immunogen Sequence:
Yeast
Datasheets/Manuals:
Printable datasheet for anti-HIST3H3 (OADC00278) antibody
Target Post-Translational Modification:
Tri-Methyl-Lys9
Specificity:
Selected using tailored phage-display libraries, and produced in E.coli eliminating animals from the antibody-production process. This recombinant antibody shows superior specificity and affinity as well as no lot-to-lot variation.
Application Info:
CHIP: 0.2-1.8 ug/CHIP
IF: (Hattori T. et al., 2013)
Gene Symbol:
HIST3H3
Official Gene Full Name:
histone cluster 3, H3
Alias Symbols:
H3t, H3.4, H3/g, H3FT
NCBI Gene Id:
8290; 8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968
Protein Name:
histone H3.1t
Description of Target:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Swissprot Id:
Q16695
Protein Accession #:
NP_003484.1
Nucleotide Accession #:
NM_003493.2
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HIST3H3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HIST3H3.

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