Histone H3 Antibody (Phospho-Ser10) (OAED00032)

Catalog No: OAED00032

Size:100UG

Western blot analysis of MW marker (1), untreated Jurkat (2), and calyculin A-treated Jurkat (3) cell lysates probed with Histone H3 (pSer10) pAb.

Product Info

• Predicted Species Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Application: Western blot
• Reconstitution and Storage: Long Term Storage : -20C
  
• Immunogen: Synthetic peptide corresponding to human Histone H3 phosphorylated at Ser10.
• Specificity: Recognizes human, mouse (weak), rat (weak), chicken (weak), Drosophila (weak), monkey (weak), pig (weak) and rabbit (weak) Histone H3.
• Formulation: Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
• Purity: Protein A affinity purified.
  
• Application Info: Western Blot
  Optimal conditions must be determined individually for each application.

Target Info

• Gene Symbol: H3-3A|H3-3B|H3C1|H3C10|H3C11|H3C12|H3C13|H3C14|H3C15|H3C2|H3C3|H3C4|H3C6|H3C7|H3C8
• Gene Full Name: H3 clustered histone 1|H3 clustered histone 10|H3 clustered histone 11|H3 clustered histone 12|H3 clustered histone 13|H3 clustered histone 14|H3 clustered histone 15|H3 clustered histone 2|H3 clustered histone 3
• Alias Symbols: H3;H3 histone family member 3A;H3 histone family member 3B;H3 histone family, member A;H3 histone family, member B;H3 histone family, member C;H3 histone family, member D;H3 histone family, member F;H3 histone family, member H;H3 histone family, member I;H3 histone family, member J;H3 histone family, member K;H3 histone family, member L;H3 histone family, member M;H3 histone, family 2;H3 histone, family 3A;H3 histone, family 3B (H3.3B);H3.1;H3.2;H3.3A;H3.3B;H3.f;H3/A;H3/b;H3/c;H3/d;H3/f;H3/h;H3/i;H3/j;H3/k;H3/l;H3/M;H3/n;H3/o;H3-3A;H3-3B;H3C1;H3C10;H3C11;H3C12;H3C13;H3C14;H3C15;H3C2;H3C3;H3C4;H3C6;H3C7;H3C8;H3-clustered histone 13;H3-clustered histone 14;H3-clustered histone 15;H3F1K;H3F2;H3F3;H3F3A;H3F3B;H3FA;H3FB;H3FC;H3FD;H3FF;H3FH;H3FI;H3FJ;H3FK;H3FL;H3FM;H3FN;HIST1H3A;HIST1H3B;HIST1H3C;HIST1H3D;HIST1H3E;HIST1H3F;HIST1H3G;HIST1H3H;HIST1H3I;HIST1H3J;HIST2H3A;HIST2H3C;HIST2H3D;histone 1, H3a;histone 1, H3b;histone 1, H3c;histone 1, H3d;histone 1, H3e;histone 1, H3f;histone 1, H3g;histone 1, H3h;histone 1, H3i;histone 1, H3j;histone 2, H3a;histone 2, H3c;histone 2, H3d;histone cluster 1 H3 family member a;histone cluster 1 H3 family member b;histone cluster 1 H3 family member c;histone cluster 1 H3 family member d;histone cluster 1 H3 family member e;histone cluster 1 H3 family member f;histone cluster 1 H3 family member g;histone cluster 1 H3 family member h;histone cluster 1 H3 family member i;histone cluster 1 H3 family member j;histone cluster 1, H3a;histone cluster 1, H3b;histone cluster 1, H3c;histone cluster 1, H3d;histone cluster 1, H3e;histone cluster 1, H3f;histone cluster 1, H3g;histone cluster 1, H3h;histone cluster 1, H3i;histone cluster 1, H3j;histone cluster 2 H3 family member a;histone cluster 2 H3 family member c;histone cluster 2 H3 family member d;histone cluster 2, H3a;histone cluster 2, H3c;histone cluster 2, H3d;histone H3.1;histone H3.2;histone H3.3;histone H3/a;histone H3/b;histone H3/c;histone H3/d;histone H3/f;histone H3/h;histone H3/i;histone H3/j;histone H3/k;histone H3/l;histone H3/m;histone H3/o.
• NCBI Gene Id: 126961|3020|3021|333932|653604|8350|8351|8352|8353|8354|8355|8356|8357|8358|8968
• Protein Name: Histone H3.1|Histone H3.2|Histone H3.3
• Description of Target: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
• Uniprot ID: P68431|P84243|Q71DI3
• Protein Accession #: NP_038576.1; NP_473386.1; NP_783584.1; NP_835510.1; NP_835511.1; NP_835512.1; NP_835587.1; NP_835734.2
• Nucleotide Accession #: NM_013548.4; NM_054045.4; NM_175653.2; NM_178203.2; NM_178204.2; NM_178205.2; NM_178215.2; NM_178216.3