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Histone H3 Antibody (Methyl-Lys79) (OADC00110)

50ug
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
Clonality:
Polyclonal
Host:
Rabbit
Conjugation:
Unconjugated
Application:
CHIP, DB, WB
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-105519 from Santa Cruz Biotechnology.
Purification:
Affinity purified
Predicted Homology Based on Immunogen Sequence:
Yeast
Concentration:
1.66 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-HIST3H3 (OADC00110) antibody
Preservative:
0.05% Sodium Azide and 0.05% ProClin 300.
Target Post-Translational Modification:
Methyl-Lys79
Specificity:
Polyclonal antibody raised in rabbit against histone H3 containing the monomethylated lysine 79 (H3K79me1), using a KLH-conjugated synthetic peptide.
Application Info:
CHIP: 1 - 2 ug/CHIP
ELISA: 1:500
Dot Blotting: 1:20,000
Western Blotting: 1:200
Gene Symbol:
HIST3H3
Official Gene Full Name:
histone cluster 3, H3
Alias Symbols:
H3t, H3.4, H3/g, H3FT
NCBI Gene Id:
8290; 8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968
Protein Name:
histone H3.1t
Description of Target:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Swissprot Id:
P68431
Protein Accession #:
NP_003520.1
Nucleotide Accession #:
NM_003529.2
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HIST3H3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HIST3H3.

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