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Histone H3 Antibody (Di-Methyl-Lys4) (OADC00098)

Catalog#: OADC00098
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species ReactivityHuman
Product FormatLiquid. Provided in PBS containing 0.05% azide.
ApplicationCHIP, WB, IF
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
Replacement ItemThis antibody may replace item sc-105519 from Santa Cruz Biotechnology.
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceA. Nidulansan
Concentration1 mg/mL
Datasheets/ManualsPrintable datasheet for anti-HIST3H3 (OADC00098) antibody
Preservative0.05% Sodium Azide
Target Post-Translational ModificationDi-Methyl-Lys4
SpecificityMonoclonal antibody raised in mouse against histone H3, dimethylated at lysine 4 (H3K4me2), using a KLH-conjugated synthetic peptide.
Application InfoCHIP: 1 ug/CHIP
ELISA: 1:5,000
Western Blotting: 1:1,000
IF: 1:500
Gene SymbolHIST3H3
Official Gene Full Namehistone cluster 3, H3
Alias SymbolsH3t, H3.4, H3/g, H3FT
NCBI Gene Id8290; 8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968
Protein Namehistone H3.1t
Description of TargetHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Swissprot IdP68431
Protein Accession #NP_003520.1
Nucleotide Accession #NM_003529.2
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express HIST3H3.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express HIST3H3.
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