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Histone H3 Antibody (Acetyl-Lys9) (OADC00116)

50ug
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. PBS containing 0.05% azide
Clonality:
Monoclonal
Isotype:
IgG2b*
Host:
Mouse
Conjugation:
Unconjugated
Application:
CHIP, WB, IF
Reconstitution and Storage:
Store at -20C. For long-term storage, store at -80C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-105519 from Santa Cruz Biotechnology.
Immunogen:
Monoclonal antibody raised in mouse against histone H3 acetylated at lysine 9 (H3K9ac), using a KLH-conjugated synthetic peptide.
Purification:
Protein A purified
Concentration:
1 ug/ul
Datasheets/Manuals:
Printable datasheet for anti-HIST3H3 (OADC00116) antibody
Specificity:
Acetyl-Lys9
Application Info:
CHIP: 0.5-1 ug/ChIP
ELISA: 1:3000
WB: 1:1000~2000
IF: 1:500
Gene Symbol:
HIST3H3
Official Gene Full Name:
histone cluster 3, H3
Alias Symbols:
H3t, H3.4, H3/g, H3FT
NCBI Gene Id:
8290; 8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968
Protein Name:
histone H3.1t
Description of Target:
Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code”. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.
Swissprot Id:
P68431
Protein Accession #:
NP_003520.1
Nucleotide Accession #:
NM_003529.2
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HIST3H3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HIST3H3.

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