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Histone H2B Antibody (Acetyl-Lys15) (OADC00070)

Catalog#: OADC00070
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species ReactivityHuman
Product FormatLiquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
ApplicationCHIP, DB, WB
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
PurificationAffinity purified
Concentration2.1 mg/mL
Datasheets/ManualsPrintable datasheet for anti-HIST1H2AE (OADC00070) antibody
Preservative0.05% Sodium Azide and 0.05% ProClin 300.
Target Post-Translational ModificationAcetyl-Lys15
SpecificityPolyclonal antibody raised in rabbit against the region of histone H2B containing the acetylated lysine 15 (H2BK15ac), using a KLH-conjugated synthetic peptide.
Application InfoCHIP: 2 ug/CHIP
ELISA: 1:1,000
Dot Blotting: 1:20,000
Western Blotting: 1:500
Gene SymbolHIST1H2AE
Official Gene Full Namehistone cluster 1, H2ae
Alias SymbolsH2A.1, H2A.2, H2A/a, H2AFA
NCBI Gene Id3012; 317772; 8335; 8338
Protein Namehistone H2A type 1-B/E
Description of TargetHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Swissprot IdP62807
Protein Accession #NP_003509.1
Nucleotide Accession #NM_003518.3
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express HIST1H2AE.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express HIST1H2AE.
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