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Histone H2A Antibody (Acetyl-Lys12) (OADC00069)

50ug
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
Clonality:
Polyclonal
Host:
Rabbit
Conjugation:
Unconjugated
Application:
CHIP, DB, WB
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Purification:
Affinity purified
Concentration:
0.82 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-HIST1H2AE (OADC00069) antibody
Preservative:
0.05% Sodium Azide and 0.05% ProClin 300.
Target Post-Translational Modification:
Acetyl-Lys12
Specificity:
Polyclonal antibody raised in rabbit against the region of histone H2B containing the acetylated lysine 12 (H2BK12ac), using a KLH-conjugated synthetic peptide.
Application Info:
CHIP: 0.5 - 1 ug/CHIP
ELISA: 1:1,000
Dot Blotting: 1:5,000
Western Blotting: 1:1,000
Gene Symbol:
HIST1H2AE
Official Gene Full Name:
histone cluster 1, H2ae
Alias Symbols:
H2A.1, H2A.2, H2A/a, H2AFA
NCBI Gene Id:
3012; 317772; 8335; 8338
Protein Name:
histone H2A type 1-B/E
Description of Target:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Swissprot Id:
P62807
Protein Accession #:
NP_003509.1
Nucleotide Accession #:
NM_003518.3
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HIST1H2AE.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HIST1H2AE.

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