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HIST1H2AI Antibody (OACA02424)

100 ug
$315.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC, CHIP
Reconstitution and Storage:
Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Immunogen:
Recombinant human Histone H2A type 1 protrin (2-130aa)
Purification:
Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence:
Human
Datasheets/Manuals:
Printable datasheet for anti-HIST1H2AG (OACA02424) antibody
Specificity:
Human
Formulation:
Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference:
[1] The human and mouse replication-dependent histone genes. Marzluff W.F., Gongidi P., Woods K.R., Jin J., Maltais L.J.Genomics 80:487-498 (2002).
[2] The DNA sequence and analysis of human chromosome 6. Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. Beck S. Nature 425:805-811 (2003).
Gene Symbol:
HIST1H2AI
Official Gene Full Name:
histone cluster 1, H2ai
Alias Symbols:
H2A/c, H2AFC
NCBI Gene Id:
8329
Protein Name:
histone H2A type 1
Description of Target:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Swissprot Id:
P0C0S8
Protein Accession #:
NP_003500.1
Nucleotide Accession #:
NM_003509.2
Protein Size (# AA):
130
Molecular Weight:
14 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HIST1H2AI.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HIST1H2AI.

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