Catalog No: ARP54761_P050
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ARP54761_P050
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HIST1H1T Antibody - middle region (ARP54761_P050)

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Datasheets/ManualsPrintable datasheet for anti-HIST1H1T (ARP54761_P050) antibody
Product Info
ReferenceOlsen,J.V., (2006) Cell 127 (3), 635-648
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Dog, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human HIST1H1T
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceDog: 92%; Human: 100%; Pig: 86%; Rabbit: 93%
Peptide SequenceSynthetic peptide located within the following region: KLSKKVIPKSTRSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKPRAT
Concentration0.5 mg/ml
Blocking PeptideFor anti-HIST1H1T (ARP54761_P050) antibody is Catalog # AAP54761 (Previous Catalog # AAPP31556)
Gene SymbolHIST1H1T
Gene Full NameHistone cluster 1, H1t
Alias SymbolsH1t, H1.6, H1FT, HIST1H1T, dJ221C16.2
NCBI Gene Id3010
Protein NameHistone H1t
Description of TargetHistones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H1T is a member of the histone H1 family. Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Uniprot IDP22492
Protein Accession #NP_005314
Nucleotide Accession #NM_005323
Protein Size (# AA)207
Molecular Weight22kDa
Protein InteractionsUBC; SUMO1; IRAK4; PRKCA; YWHAQ; POU5F1;
  1. What is the species homology for "HIST1H1T Antibody - middle region (ARP54761_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Dog, Pig, Rabbit".

  2. How long will it take to receive "HIST1H1T Antibody - middle region (ARP54761_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HIST1H1T Antibody - middle region (ARP54761_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HIST1H1T Antibody - middle region (ARP54761_P050)"?

    This target may also be called "H1t, H1.6, H1FT, HIST1H1T, dJ221C16.2" in publications.

  5. What is the shipping cost for "HIST1H1T Antibody - middle region (ARP54761_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HIST1H1T Antibody - middle region (ARP54761_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HIST1H1T Antibody - middle region (ARP54761_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "22kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HIST1H1T Antibody - middle region (ARP54761_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HIST1H1T"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HIST1H1T"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HIST1H1T"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HIST1H1T"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HIST1H1T"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HIST1H1T"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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