HIPK2 Antibody - middle region : FITC (ARP32586_P050-FITC)

Catalog No: ARP32586_P050-FITC

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB, IHC
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human HIPK2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 87%
• Peptide Sequence: Synthetic peptide located within the following region: MWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTR
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-HIPK2 (ARP32586_P050-FITC) antibody is Catalog # AAP32586
• Sample Type Confirmation:

  HIPK2 is supported by BioGPS gene expression data to be expressed in HepG2

• Publications:

  Choi, D. W. et al. Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1. J. Biol. Chem. 283, 4682-9 (2008). WB, ICC/IF, Rat, Horse, Guinea pig, Human, Dog, Mouse, Rabbit, Zebrafish, Bovine 18093972

  Steinmann, S. et al. v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300. Oncogene 28, 2446-55 (2009). WB, Rat, Horse, Guinea pig, Human, Dog, Mouse, Rabbit, Zebrafish, Bovine 19448669

Target Info

• Gene Symbol: HIPK2
• Gene Full Name: Homeodomain interacting protein kinase 2
• Alias Symbols: PRO0593
• NCBI Gene Id: 28996
• Protein Name: Homeodomain-interacting protein kinase 2
• Description of Target: HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
• Uniprot ID: Q9H2X6
• Protein Accession #: NP_073577
• Nucleotide Accession #: NM_022740
• Protein Size (# AA): 1198
• Molecular Weight: 120kDa
• Protein Interactions: UBC; TP53; SIAH2; XAF1; AATF; SUMO1; MDM2; AXIN1; SIAH1; MBP; DAXX; MKNK1; MECP2; ZBTB4; HIPK2; DCAF7; DYRK1B; MAP3K1; DYRK1A; FBXO3; CBX4; SUMO2; SUMO3; PML; PAX6; CHMP4B; SENP2; SENP1; UBE2I; HIST2H2BE; CXCL1; SIAH1P1; WSB1; MYBL2; MYBL1; NLK; MAP3K7; M