HIF1A Protein (OPPA02575)

Catalog No: OPPA02575 (Formerly GWB-BSP502)

Size:1UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid20mM Tris buffer (pH 8.0), 20% glycerol, 1mM DTT, 0.2M NaCl and 1mM EDTA
• Host: E. Coli
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
• Purification: Purified by proprietary chromatographic techniques
• Concentration: 0.25 mg/ml
• Purity: Greater than 80.0% as determined by SDS-PAGE.
• Peptide Sequence: 85 a.a.
• Protein Sequence: MGSSHHHHHH SSGLVPRGSH MEGAGGANDK KKISSERRKE KSRDAARSRR SKESEVFYEL AHQLPLPHNV SSHLDKASVM RLTISYLRVR KLLDAGDLDI EDDMK.
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: HIF1A
• Alias Symbols: HIF1, MOP1, PASD8, HIF-1A, bHLHe78, HIF-1alpha, HIF1-ALPHA, HIF-1-alpha
• NCBI Gene Id: 3091
• Protein Name: Hypoxia-inducible factor 1-alpha
• Description of Target: HIF1A has a role as a master transcriptional monitor of the adaptive response to hypoxia. Under hypoxic conditions HIF1A activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and genes whose protein products increase oxygen release or facilitate metabolic adaptation to hypoxia. HIF1A functions as an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. HIF1A Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 105 amino acids (1-85 a.a.).
• Uniprot ID: Q16665
• Protein Accession #: NP_001230013.1
• Protein Size (# AA): Recombinant
• Molecular Weight: 12 kDa