HGF Recombinant Protein (OPCD04597)

Catalog No: OPCD04597

HGF Recombinant Protein (OPCD04597) using SDS-PAGE

HGF Recombinant Protein (OPCD04597) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Leu923-Cys1197
  Subcellular Location: Membrane; Single-pass type I membrane protein. Cell junction, hemidesmosom
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: ITGB4
• Gene Full Name: integrin subunit beta 4
• Alias Symbols: CD104;CD104 antigen;GP150;integrin beta-4.
• NCBI Gene Id: 3691
• Protein Name: Integrin beta-4
• Description of Target: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).
• Uniprot ID: P16144
• Protein Accession #: NP_000592.3
• Nucleotide Accession #: NM_000601.5
• Protein Size (# AA): Leu923~Cys1197
• Molecular Weight: 36kDa