HEYL Antibody - N-terminal region : FITC (ARP31866_T100-FITC)

Catalog No: ARP31866_T100-FITC

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HEYL
• Predicted Homology Based on Immunogen Sequence: Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKRRGI
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-HEYL (ARP31866_T100-FITC) antibody is Catalog # AAP31866 (Previous Catalog # AAPP02661)
• Reference: Nakagawa,O., et al., (2000) McFadden,D.G., Nakagawa,M., Proc. Natl. Acad. Sci. U.S.A. 97 (25), 13655-13660
• Publications:

  Morrow, D. et al. Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A. Arterioscler. Thromb. Vasc. Biol. 29, 1112-8 (2009). WB, IHC, Rat, Guinea pig, Mouse, Human, Dog, Bovine, Horse 19407245

Target Info

• Gene Symbol: HEYL
• Gene Full Name: Hairy/enhancer-of-split related with YRPW motif-like
• Alias Symbols: HEY3, HRT3, HESR3, bHLHb33
• NCBI Gene Id: 26508
• Protein Name: Hairy/enhancer-of-split related with YRPW motif-like protein
• Description of Target: HEYL belongs to hairy-related bHLH transcription factor family. HEY genes are candidates for several human or mouse disease loci.
• Uniprot ID: Q9NQ87
• Protein Accession #: NP_055386
• Nucleotide Accession #: NM_014571
• Protein Size (# AA): 328
• Molecular Weight: 35kDa
• Protein Interactions: RPGRIP1; RBPMS; MDFI; ZNF512B; HIPK3; LAPTM5; SKIL; ATXN1; PPP1CA; SMAD9; SMAD7; SMAD3; HTT; APP; UBC; SP8; ATF7IP; HAND2; HAND1;