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Catalog No: ARP61100_P050
Price: $0.00
SKU
ARP61100_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-HEXA (ARP61100_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human HEXA
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 85%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 93%; Sheep: 93%
Peptide SequenceSynthetic peptide located within the following region: WKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAV
Concentration0.5 mg/ml
Blocking PeptideFor anti-HEXA (ARP61100_P050) antibody is Catalog # AAP61100 (Previous Catalog # AAPP47265)
Subunitalpha
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
SPR Affinity Characterization Avivasheild
Gene SymbolHEXA
Gene Full NameHexosaminidase A (alpha polypeptide)
Alias SymbolsTSD
NCBI Gene Id3073
Protein NameBeta-hexosaminidase subunit alpha
Description of TargetThis gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Uniprot IDP06865
Protein Accession #NP_000511
Nucleotide Accession #NM_000520
Protein Size (# AA)529
Molecular Weight61 kDa
Protein InteractionsH2AFV; WDR61; UBA6; UBR7; C9orf78; HERC4; FKBP9; PDCD10; NUBP2; GTF3C4; HIST1H2BO; XPNPEP1; EZR; RAD23A; PCNA; KTN1; HK1; GDI1; CAPZB; AHCY; ACAT2; FBXO6; H2AFX; GM2A; USP22;
  1. What is the species homology for "HEXA Antibody - C-terminal region (ARP61100_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep".

  2. How long will it take to receive "HEXA Antibody - C-terminal region (ARP61100_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HEXA Antibody - C-terminal region (ARP61100_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HEXA Antibody - C-terminal region (ARP61100_P050)"?

    This target may also be called "TSD" in publications.

  5. What is the shipping cost for "HEXA Antibody - C-terminal region (ARP61100_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HEXA Antibody - C-terminal region (ARP61100_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HEXA Antibody - C-terminal region (ARP61100_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "61 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HEXA Antibody - C-terminal region (ARP61100_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HEXA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HEXA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HEXA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HEXA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HEXA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HEXA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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