HES1 Recombinant Protein (OPCD03842)

Catalog No: OPCD03842

HES1 Recombinant Protein (OPCD03842) using SDS-PAGE

HES1 Recombinant Protein (OPCD03842) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Val21-Asn251
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: HES1
• Gene Full Name: hes family bHLH transcription factor 1
• Alias Symbols: bHLHb39;class B basic helix-loop-helix protein 39;Hairy and enhancer of split 1;hairy homolog;hairy-like protein;HES-1;HHL;HRY;transcription factor HES-1.
• NCBI Gene Id: 3280
• Protein Name: Transcription factor HES-1
• Description of Target: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
• Uniprot ID: Q14469
• Protein Accession #: NP_005515.1
• Nucleotide Accession #: NM_005524.3
• Protein Size (# AA): Val21~Asn251
• Molecular Weight: 28kDa