Catalog No: ARP56008_P050
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ARP56008_P050
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Datasheets/ManualsPrintable datasheet for anti-ERVFRD-1 (ARP56008_P050) antibody
Product Info
Publications

OVO-like 1 regulates progenitor cell fate in human trophoblast development. Proc Natl Acad Sci U S A. 112, E6175-84 (2015). 26504231

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Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human HERV-FRD
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman: 100%
Peptide SequenceSynthetic peptide located within the following region: TGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPNLKG
Concentration0.5 mg/ml
Blocking PeptideFor anti-ERVFRD-1 (ARP56008_P050) antibody is Catalog # AAP56008 (Previous Catalog # AAPP37414)
ReferenceMalassine,A., (er) Retrovirology 5, 6 (2008)
Gene SymbolERVFRD-1
Gene Full NameEndogenous retrovirus group FRD, member 1
Alias SymbolsenvFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD
NCBI Gene Id405754
Protein NameHERV-FRD_6p24.1 provirus ancestral Env polyprotein
Description of TargetRetroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].
Uniprot IDP60508
Protein Accession #NP_997465
Nucleotide Accession #NM_207582
Protein Size (# AA)538
Molecular Weight60kDa
Protein InteractionsAPP;
  1. What is the species homology for "HERV-FRD Antibody - N-terminal region (ARP56008_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "HERV-FRD Antibody - N-terminal region (ARP56008_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HERV-FRD Antibody - N-terminal region (ARP56008_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HERV-FRD Antibody - N-terminal region (ARP56008_P050)"?

    This target may also be called "envFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD" in publications.

  5. What is the shipping cost for "HERV-FRD Antibody - N-terminal region (ARP56008_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HERV-FRD Antibody - N-terminal region (ARP56008_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HERV-FRD Antibody - N-terminal region (ARP56008_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "60kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HERV-FRD Antibody - N-terminal region (ARP56008_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ERVFRD-1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ERVFRD-1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ERVFRD-1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ERVFRD-1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ERVFRD-1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ERVFRD-1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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