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HDAC9 Antibody (OAAJ06909)

100 uL
$289.00
In Stock
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Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Clonality:
Polyclonal
Host:
Rabbit
Application:
WB, IHC
Reconstitution and Storage:
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Gene Symbol:
HDAC9
NCBI Gene Id:
9734
Protein Name:
Histone deacetylase 9
Swissprot Id:
Q9UKV0
Protein Accession #:
NP_001191073
Nucleotide Accession #:
NM_001204144
Alias Symbols:
DKFZp779K1053, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, Histone deacetylase 7B, Histone deacetylase 9, Histone deacetylase-related protein, KIAA0744, MEF2-interacting transcription repressor MITR, MITR
Description of Target:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.
Molecular Weight:
111 kDa
Purification:
Immunogen affinity chromatography
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HDAC9.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HDAC9.
Immunogen:
A synthetic peptideof human HDAC9
Concentration:
1 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-HDAC9 (OAAJ06909) antibody

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