HDAC6 Recombinant Protein (OPCD03826)

Catalog No: OPCD03826

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gln1038-Gln1204
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: HDAC6
• Gene Full Name: histone deacetylase 6
• Alias Symbols: CPBHM;HD6;histone deacetylase 6;JM21;PPP1R90;protein phosphatase 1, regulatory subunit 90;tubulin-lysine deacetylase HDAC6.
• NCBI Gene Id: 10013
• Protein Name: Histone deacetylase 6
• Description of Target: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
• Uniprot ID: Q9UBN7
• Protein Accession #: NP_001308155.1
• Nucleotide Accession #: NM_001321226.1
• Protein Size (# AA): Gln1038~Gln1204
• Molecular Weight: 21kDa