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HDAC3 Antibody (OADC00269)

50ug
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
Clonality:
Monoclonal
Isotype:
IgG1
Host:
Mouse
Conjugation:
Unconjugated
Application:
CHIP, IF
Reconstitution and Storage:
Store at -20C; for long storage, store at -80C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-11417 from Santa Cruz Biotechnology.
Immunogen:
Monoclonal antibody raised in mouse against human HDAC3 (Histone deacetylase 3), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal region of the protein.
Purification:
Protein A/G purified
Concentration:
2 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-HDAC3 (OADC00269) antibody
Specificity:
Mouse monoclonal antibody raised against HDAC3
Application Info:
ChIP: 2 ug/ChIP
IF: 1:500
Gene Symbol:
HDAC3
Official Gene Full Name:
histone deacetylase 3
Alias Symbols:
HD3, RPD3, RPD3-2
NCBI Gene Id:
8841;
Protein Name:
histone deacetylase 3
Description of Target:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Swissprot Id:
O15379
Protein Accession #:
NP_003874.2
Nucleotide Accession #:
NM_003883.3
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HDAC3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HDAC3.

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