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Catalog No: OAAJ07336
Size:100 uL
Price: $319.00
SKU
OAAJ07336
Availability: Domestic: within 2-3 week delivery | International: 2-3 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-HDAC3 (OAAJ07336) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageStore at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
ImmunogenA synthetic peptideof human HDAC3
PurificationImmunogen affinity chromatography
Concentration1 mg/mL
Gene SymbolHDAC3
Alias SymbolsHD3, RPD3, KDAC3, RPD3-2
NCBI Gene Id8841
Description of TargetResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation. Contributes, together with XBP1 isoform 1, to the activation of NFE2L2-mediated HMOX1 transcription factor gene expression in a PI3K/mTORC2/Akt-dependent signaling pathway leading to endothelial cell (EC) survival under disturbed flow/oxidative stress.
Uniprot IDO15379
Protein Accession #NP_003874
Nucleotide Accession #NM_003883
Molecular Weight49 kDa
  1. What is the species homology for "HDAC3 Antibody (OAAJ07336)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "HDAC3 Antibody (OAAJ07336)"?

    This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".

  3. What buffer format is "HDAC3 Antibody (OAAJ07336)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HDAC3 Antibody (OAAJ07336)"?

    This target may also be called "HD3, RPD3, KDAC3, RPD3-2" in publications.

  5. What is the shipping cost for "HDAC3 Antibody (OAAJ07336)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HDAC3 Antibody (OAAJ07336)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HDAC3 Antibody (OAAJ07336)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "49 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HDAC3 Antibody (OAAJ07336)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HDAC3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HDAC3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HDAC3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HDAC3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HDAC3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HDAC3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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