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More Information
Predicted Species ReactivityHuman
Product FormatLiquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
ApplicationCHIP, WB, ARRAY, IF
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
Replacement ItemThis antibody may replace item sc-125435 from Santa Cruz Biotechnology.
PurificationAffinity purified
Predicted Homology Based on Immunogen SequenceMouse
Concentration1.73 mg/mL
Datasheets/ManualsPrintable datasheet for anti-HDAC1 (OADC00144) antibody
Preservative0.05% Sodium Azide and 0.05% ProClin 300.
SpecificityPolyclonal antibody raised in rabbit against the C-terminal region of human HDAC1 (Histone deacetylase 1), using a KLH-conjugated synthetic peptide.
Application InfoCHIP: 2 ug/CHIP
ELISA: 1:4,000
Western Blotting: 1:1,000
Protein array 1:100,000
Immunofluorescence: 1:500
Gene SymbolHDAC1
Official Gene Full Namehistone deacetylase 1
Alias SymbolsHD1, RPD3, GON-10, RPD3L1
NCBI Gene Id3065;
Protein Namehistone deacetylase 1
Description of TargetHistone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Swissprot IdQ13547
Protein Accession #NP_004955.2
Nucleotide Accession #NM_004964.2
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express HDAC1.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express HDAC1.
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