Size:100 ug
$315.00
In Stock
SKU
OACA02422
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HDAC1 Antibody (OACA02422)

Catalog#: OACA02422
Domestic: within 1-2 weeks delivery | International: 1-2 weeks
More Information
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, IHC, CHIP
Reconstitution and StorageStore at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement ItemThis antibody may replace item sc-125435, HPA029693
ImmunogenRecombinant human HDAC1 protein
PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen SequenceHuman, Mouse
Datasheets/ManualsPrintable datasheet for anti-HDAC1 (OACA02422) antibody
SpecificityHuman
FormulationProvided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference[1] MEF-2 function is modified by a novel co-repressor, MITR. Sparrow D.B., Miska E.A., Langley E., Reynaud-Deonauth S., Kotecha S., Towers N., Spohr G., Kouzarides T., Mohun T.J.EMBO J. 18:5085-5098 (1999).
[2] BCoR, a novel corepressor involved in BCL-6 repression. Huynh K.D., Fischle W., Verdin E., Bardwell V.J.Genes Dev. 14:1810-1823 (2000).
Gene SymbolHDAC1
Official Gene Full Namehistone deacetylase 1
Alias SymbolsHD1, RPD3, GON-10, RPD3L1
NCBI Gene Id3065
Protein Namehistone deacetylase 1
Description of TargetHistone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Swissprot IdQ13547
Protein Accession #NP_004955.2
Nucleotide Accession #NM_004964.2
Protein Size (# AA)482
Molecular Weight55 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express HDAC1.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express HDAC1.
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