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HDAC1 Antibody (OACA02422)

100 ug
$315.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC, CHIP
Reconstitution and Storage:
Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item:
This antibody may replace item sc-125435, HPA029693
Immunogen:
Recombinant human HDAC1 protein
Purification:
Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence:
Human, Mouse
Datasheets/Manuals:
Printable datasheet for anti-HDAC1 (OACA02422) antibody
Specificity:
Human
Formulation:
Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference:
[1] MEF-2 function is modified by a novel co-repressor, MITR. Sparrow D.B., Miska E.A., Langley E., Reynaud-Deonauth S., Kotecha S., Towers N., Spohr G., Kouzarides T., Mohun T.J.EMBO J. 18:5085-5098 (1999).
[2] BCoR, a novel corepressor involved in BCL-6 repression. Huynh K.D., Fischle W., Verdin E., Bardwell V.J.Genes Dev. 14:1810-1823 (2000).
Gene Symbol:
HDAC1
Official Gene Full Name:
histone deacetylase 1
Alias Symbols:
HD1, RPD3, GON-10, RPD3L1
NCBI Gene Id:
3065
Protein Name:
histone deacetylase 1
Description of Target:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Swissprot Id:
Q13547
Protein Accession #:
NP_004955.2
Nucleotide Accession #:
NM_004964.2
Protein Size (# AA):
482
Molecular Weight:
55 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HDAC1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HDAC1.

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