HCV Core 22kDa Protein (OPPA00952)

Catalog No: OPPA00952 (Formerly GWB-396BFD)

Size:100UG

Product Info

• Predicted Species Reactivity: Hepatitis C Virus
• Product Format: 20mM Tris-Hcl pH 8, 8M urea and 10mM B-ME.
• Application: ELISA, WB
  Product Introduction: HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
  Product Description: The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-192. The Rhodamine labeled protein is fused with b-galactosidase (114 kDa) at N-terminus.
• Reconstitution and Storage: HCV-Core protein is shipped at ambient temperature. Upon arrival, Store at -20C.
  Stability: Five years frozen. One month in solution at room temperature.
• Purity: HCV-Core protein is >95% pure as determined by 10% PAGE (coomassie staining).
  Purification: HCV-Core protein was purified by proprietary chromatographic technique.
• Specificity: Immunoreactive with sera of HCV-infected individuals.
• Application Info: HCV Core antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.

Target Info

• Gene Symbol: HCV
• Alias Symbols: HCV Core 22kDa, Rhodamine, Hepatitis C Virus Core 22kDa, Rhodamine Recombinant
• Description of Target: Recombinant Hepatitis C Virus Nucleocapsid (core) 22kDa, Rhodamine Labeled
• Protein Size (# AA): Recombinant