HBP Antibody (OADB00296)

Catalog No: OADB00296

Size:200 uL

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Monoclonal
• Clone: B-R37
• Isotype: Mouse IgG2b kappa light chain
• Host: Human
• Reconstitution and Storage: Store at +2-8C for 12 months. For longer storage freeze aliquots
• Purification: Ion exchange chromatography
• Concentration: 1 ug/uL
• Specificity: Recognises both natural and recombinant human HBP
• Formulation: Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
• Storage Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
• Biological Activity: Recognises soluble antigen

Target Info

• Gene Symbol: HBP
• Gene Full Name: azurocidin 1
• Alias Symbols: AZU, HBP, NAZC, hHBP, AZAMP, CAP37, HUMAZUR
• NCBI Gene Id: 566
• Protein Name: azurocidin
• Description of Target: Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
• Uniprot ID: P20160
• Protein Accession #: NP_001691.1
• Nucleotide Accession #: NM_001700.4
• Molecular Weight: 27 kDa