Search Antibody, Protein, and ELISA Kit Solutions

HBB Antibody - C-terminal region (OAAB07804)

  • Catalog#: OAAB07804
  • Inquire
400ul
$320.00
Discontinued
Request Bulk Order Quote
Gene Symbol:
HBB
NCBI Gene Id:
3043
Protein Name:
Hemoglobin subunit beta
Swissprot Id:
P68871
Protein Accession #:
NP_000509.1
Alias Symbols:
HBB, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7
Replacement Item:
This antibody may replace item sc-130320 from Santa Cruz Biotechnology.
Description of Target:
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Molecular Weight:
16 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Application:
WB, FC, IHC-P
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HBB.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HBB.
Immunogen:
This HBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-107 amino acids from the C-terminal region of human HBB.
Predicted Homology Based on Immunogen Sequence:
Cow, Mouse, Pig, Rabbit, Rat, Chicken
Product Format:
Liquid. PBS with 0.09% (W/V) sodium azide.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 months. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals:
Printable datasheet for OAAB07804
Isotype:
Ig
Intended Use:
HBB Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Application Info:
WB 1:2000
FC 1:10 - 50
IHC-P 1:10 - 50
Additional Information:
Function: Involved in oxygen transport from the lung to the various peripheral tissues. Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation.
Tissue Location: Red blood cells.
Publications:

Brown, N; Alkhayer, K; Clements, R; Singhal, N; Gregory, R; Azzam, S; Li, S; Freeman, E; McDonough, J; Neuronal Hemoglobin Expression and Its Relevance to Multiple Sclerosis Neuropathology. 59, 1-17 (2016). WB, FC, IHC-P, Human 26809286

Product Reviews

Tell us what you think about this item!

Write A Review
    Please, wait...