HAND1 Antibody (Phospho-Ser98) (OASG03264)

Catalog No: OASG03264

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human HAND1 around the phosphorylation site of S98. Location: 40-120aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser98
• Specificity: Phospho-HAND1 (S98) Polyclonal Antibody detects endogenous levels of HAND1 protein only when phosphorylated at S98.
• Application Info: IHC 1:100-1:300; ELISA 1:10000;

Target Info

• Gene Symbol: HAND1
• Gene Full Name: heart and neural crest derivatives expressed 1
• Alias Symbols: Hxt, eHand, Thing1, bHLHa27
• NCBI Gene Id: 9421; 15110; 59112
• Description of Target: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
• Uniprot ID: O96004, Q64279, P97832
• Molecular Weight: 24 kDa