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H2AFX Antibody (Phospho-Ser140) (OABF01183)
| Datasheets/Manuals | Printable datasheet for H2AFX Antibody (Phospho-Ser140) (OABF01183) |
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| Predicted Species Reactivity | Bovine|Dog|Horse|Human|Mouse|Other|Porcine|Rabbit|Rat |
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| Product Format | Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot |
| Additional Information | Subcellular location: Nucleus |
| :: | Modification: Phosphorylation (Ser140) |
| Reconstitution and Storage | -20°C |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Histone H2AX around the phosphorylation site of Ser140 |
| Purification | Protein A Purified |
| Concentration | 1 ug/ul |
| Application Info | IHC-P: : 1:100 - 500 |
| Gene Symbol | H2AX |
|---|---|
| Gene Full Name | H2A.X variant histone |
| Alias Symbols | H2A histone family member X;H2A.X;H2A/X;H2AFX;H2AX histone;histone H2A.x;histone H2AX. |
| NCBI Gene Id | 3014 |
| Protein Name | Histone H2AX |
| Description of Target | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. |
| Uniprot ID | P16104 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "H2AFX Antibody (Phospho-Ser140) (OABF01183)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Dog|Horse|Human|Mouse|Other|Porcine|Rabbit|Rat".
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How long will it take to receive "H2AFX Antibody (Phospho-Ser140) (OABF01183)"?
This item is available "3 to 5 business days.".
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What buffer format is "H2AFX Antibody (Phospho-Ser140) (OABF01183)" provided in?
This item is provided in "Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "H2AFX Antibody (Phospho-Ser140) (OABF01183)"?
This target may also be called "H2A histone family member X;H2A.X;H2A/X;H2AFX;H2AX histone;histone H2A.x;histone H2AX." in publications.
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What is the shipping cost for "H2AFX Antibody (Phospho-Ser140) (OABF01183)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "H2AFX Antibody (Phospho-Ser140) (OABF01183)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "H2AFX Antibody (Phospho-Ser140) (OABF01183)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "H2AFX Antibody (Phospho-Ser140) (OABF01183)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "H2AX"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "H2AX"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "H2AX"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "H2AX"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "H2AX"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "H2AX"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
