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H2AFX Antibody (Acetyl-Lys5) (OASG03380)

100 uL
$215.00
In Stock
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Gene Symbol:
H2AFX
Official Gene Full Name:
H2A histone family, member X
NCBI Gene Id:
3014; 15270;
Swissprot Id:
P16104, P27661
Alias Symbols:
H2AFX, H2AX, Histone H2A.x, H2a/x
Description of Target:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express H2AFX.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express H2AFX.
Immunogen:
Synthetic Peptide
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. 1 mg/mL in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-H2AFX (OASG03380) antibody
Target Post-Translational Modification:
Acetyl-Lys5
Specificity:
The antibody detects endogenous Histone H2A.X (Acetyl Lys5) protein.
Isotype:
IgG
Application Info:
WB 1:1000-2000

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