H1N1 Hemagglutinin Antibody (OAPB01364)

Catalog No: OAPB01364

Size:100UG

Product Info

• Predicted Species Reactivity: Influenza A Virus|Virus
• Product Format: Liquid. Seasonal H1N1 Hemagglutinin Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Monoclonal
• Isotype: IgG₁
• Host: Mouse
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Western blot
• Reconstitution and Storage: Seasonal H1N1 Hemagglutinin monoclonal antibody can be stored at -20°C, stable for one year.
• Immunogen: Mouse monoclonal Hemagglutinin antibody was raised against a synthetic peptide from the Hemagglutinin protein.
• Purification: Affinity Purified
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-H1N1 Hemagglutinin (OAPB01364) antibody is Catalog # OEPB02977
• Application Info: Hemagglutinin antibody can be used for the detection of the Hemagglutinin protein from the H1N1 strain of Seasonal influenza A in ELISA. It will also detect 2 ng of free peptide at 1 mg/ml and does not cross-react with peptide corresponding to the swine-origin influenza A (S-OIV, H1N1) Hemagglutinin. (Optimal dilution should be determined by user)
• Reference: Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team, Dawood FS, Jain S, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N. Engl. J. Med. 2009; 360:2605-15.;Morens DM, Taubenberger JK, and Fauci AS. The Persistent Legacy of the 1918 Influenza Virus. N. Engl. J. Med. 2009; Jun 29. ;

Target Info

• Gene Symbol: H1N1 Hemagglutinin
• Gene Full Name: Hemagglutinin
• Protein Name: Hemagglutinin|hemagglutinin [Influenza A virus (A/Brisbane/59/2007(H1N1))]
• Description of Target: Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
• Uniprot ID: Q67010
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/ACA28844