Catalog No: ARP53204_P050
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ARP53204_P050
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Datasheets/ManualsPrintable datasheet for anti-H1FOO (ARP53204_P050) antibody
Product Info
ReferenceTanaka,M., (2005) Biol. Reprod. 72 (1), 135-142
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human H1FOO
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman: 100%; Rat: 83%
Peptide SequenceSynthetic peptide located within the following region: MAPGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGR
Concentration0.5 mg/ml
Blocking PeptideFor anti-H1FOO (ARP53204_P050) antibody is Catalog # AAP53204 (Previous Catalog # AAPP36341)
Gene SymbolH1FOO
Gene Full NameH1 histone family, member O, oocyte-specific
Alias SymbolsH1.8, H1oo, osH1, H1FOO
NCBI Gene Id132243
Protein NameHistone H1oo
Description of TargetH1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.
Uniprot IDQ8IZA3
Protein Accession #NP_722575
Nucleotide Accession #NM_153833
Protein Size (# AA)346
Molecular Weight36kDa
  1. What is the species homology for "H1FOO Antibody - N-terminal region (ARP53204_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Rat".

  2. How long will it take to receive "H1FOO Antibody - N-terminal region (ARP53204_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "H1FOO Antibody - N-terminal region (ARP53204_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "H1FOO Antibody - N-terminal region (ARP53204_P050)"?

    This target may also be called "H1.8, H1oo, osH1, H1FOO" in publications.

  5. What is the shipping cost for "H1FOO Antibody - N-terminal region (ARP53204_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "H1FOO Antibody - N-terminal region (ARP53204_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "H1FOO Antibody - N-terminal region (ARP53204_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "36kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "H1FOO Antibody - N-terminal region (ARP53204_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "H1FOO"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "H1FOO"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "H1FOO"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "H1FOO"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "H1FOO"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "H1FOO"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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