GZMB Recombinant Protein (OPCD03769)

Catalog No: OPCD03769

GZMB Recombinant Protein (OPCD03769) using SDS-PAGE

GZMB Recombinant Protein (OPCD03769) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ile21-Tyr247
  Subcellular Location: Cytoplasm
  Isoelectric Point: 9.7
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 350 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: GZMB
• Gene Full Name: granzyme B
• Alias Symbols: C11;cathepsin G-like 1;CCPI;CGL1;CGL-1;CSPB;CSP-B;CTLA1;CTLA-1;CTSGL1;cytotoxic serine protease B;cytotoxic T-lymphocyte proteinase 2;fragmentin 2;Fragmentin-2;granzyme B;granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1);Granzyme-2;HLP;human lymphocyte protein;SECT;T-cell serine protease 1-3E.
• NCBI Gene Id: 3002
• Protein Name: Granzyme B
• Description of Target: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
• Uniprot ID: P10144
• Protein Accession #: NP_004122.2
• Nucleotide Accession #: NM_004131.4
• Protein Size (# AA): Ile21~Tyr247
• Molecular Weight: 31kDa