GZMA Recombinant Protein (OPCD03768)

Catalog No: OPCD03768

GZMA Recombinant Protein (OPCD03768) using SDS-PAGE

GZMA Recombinant Protein (OPCD03768) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ile29-Val260
  Subcellular Location: Secreted; Cytoplasmic granu
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Gzma
• Gene Full Name: granzyme A
• Alias Symbols: autocrine thymic lymphoma granzyme-like serine protease;AW494114;BLT esterase;Ctl;Ctla;Ctla3;Ctla-3;fragmentin-1;granzyme A;H factor;Hanukah factor;Hf;Hf1;SE;SE1;serine esterase 1;t cell-specific serine protease 1;TS;TSP;TSP1;TSP-1.
• NCBI Gene Id: 14938
• Protein Name: Granzyme A
• Description of Target: Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (By similarity).
• Uniprot ID: P11032
• Protein Accession #: NP_034500.1
• Nucleotide Accession #: NM_010370.2
• Protein Size (# AA): Ile29~Val260
• Molecular Weight: 29kDa