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Catalog No: OPPA02446 (Formerly GWB-BSP359)
Size:5UG
Price: $75.00
SKU
OPPA02446
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GUK1 Protein (OPPA02446)

Datasheets/ManualsPrintable datasheet for OPPA02446
Product Info
Predicted Species ReactivityHuman
Product FormatThe GUK1 1mg/ml protein solution contains 20mM Tris-HCL pH-8, 1mM DTT, 0.1M NaCl and 10% Glycerol. Physical appearance: Sterile Filtered colorless clear solution.
HostE. Coli
::Product Introduction: GUK1 is part of the guanylate kinase family. GUK1 occurs as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thus takes an important part in the recycling of GMP. Through its catalytic activity, GUK1 functions in regulation of the supply of guanine nucleotides to signal transduction pathways. GUK1 overexpression is related with pituitary adenocarcinomas, implicating that GUK1 is has a role in tumorigenesis.
Product Description: GUK1 Human Recombinant produced in E.Coli is a signle, non-glycosylated, polypeptide chain containing 217 amino acids (1-197 a.a.)and having a total molecular mass of 23.9 kDa. GUK1 is fused to a 20 amino acid His Tag at N-terminus and is purified by proprietary chromatographic techniques.
Reconstitution and StorageStore at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. Please avoid freeze thaw cycles.
PurityGreater than 90.0% as determined by SDS-PAGE.
Peptide SequenceMGSSHHHHHH SSGLVPRGSH MSGPRPVVLS GPSGAGKSTL LKRLLQEHSG IFGFSVSHTT RNPRPGEENG KDYYFVTREV MQRDIAAGDF IEHAEFSGNL YGTSKVAVQA VQAMNRICVL DVDLQGVRNI KATDLRPIYI SVQPPSLHVL EQRLRQRNTE TEESLVKRLA AAQADMESSK EPGLFDVVII NDSLDQAYAE LKEALSEEIK KAQRTGA.
Gene SymbolGUK1
Alias SymbolsGMK
NCBI Gene Id2987
Protein NameGuanylate kinase
Description of TargetRecombinant Human Guanylate Kinase 1
Uniprot IDQ16774
Protein Accession #NP_000849.1
Protein Size (# AA)Recombinant
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