GTF2E1 Antibody - N-terminal region (P100863_P050)

Catalog No: P100863_P050

WB Suggested Anti-GTF2E1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysateGTF2E1 is supported by BioGPS gene expression data to be expressed in 721_B

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2E1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: DHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFC
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-GTF2E1 (P100863_P050) antibody is Catalog # AAP31226 (Previous Catalog # AAPP01971)
• Sample Type Confirmation:

  GTF2E1 is supported by BioGPS gene expression data to be expressed in 721_B

• Subunit: 1

Target Info

• Reference: Okuda,M., (2008) EMBO J. 27 (7), 1161-1171
• Gene Symbol: GTF2E1
• Gene Full Name: General transcription factor IIE, polypeptide 1, alpha 56kDa
• Alias Symbols: FE, TF2E1, TFIIE-A
• NCBI Gene Id: 2960
• Protein Name: General transcription factor IIE subunit 1
• Description of Target: GTF2E1 belongs to the TFIIE alpha subunit family. It recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
• Uniprot ID: P29083
• Protein Accession #: NP_005504
• Nucleotide Accession #: NM_005513
• Protein Size (# AA): 439
• Molecular Weight: 49kDa
• Protein Interactions: UBC; AARSD1; ACBD3; XPO5; SH3GLB2; OXR1; NSUN2; RPUSD2; SNF8; EFTUD2; TTC1; SH3GL1; SARS; HARS; SRPK2; TCEA1; GTF2H1; GTF2E2; CDK7; APP; tat; GTF2F1; ELAVL1; ZSCAN1; ZBTB9; TRIM15; PCBD2; TRIM29; CBFA2T2; IKBKG; ATF7IP; TAF6; GTF2B; TRIM24; SND1; GTF2H4;