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Datasheets/Manuals | Printable datasheet for GSTP1 Antibody (OABB00137) |
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Tested Species Reactivity | Human, Mouse |
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Predicted Species Reactivity | Horse|Human|Mouse|Rat |
Product Format | Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Clonality | Polyclonal |
Clone | Polyclonal |
Isotype | Rabbit IgG |
Application | Immunohistochemistry|Western blot |
Additional Information | Notes: Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. |
:: | Background: Glutathione S-transferases pi, also known as GST3, present in all tissues and cells, with the exception of red cells, in which only erythrocyte GST(GSTe) is observed. The GST-pi gene has 7 exons and 6 introns contained within approximately 2.8 kilobases. The GST-pi gene is mapped to chromosome 11 .Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. GSTP does not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a novel and unexpected role in the toxicity of this compound. |
:: | Background: Glutathione S-transferases pi, also known as GST3, present in all tissues and cells, with the exception of red cells, in which only erythrocyte GST (GSTe) is observed. The GST-pi gene has 7 exons and 6 introns contained within approximately 2.8 kilobases. The GST-pi gene is mapped to chromosome 11 .Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. GSTP does not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a novel and unexpected role in the toxicity of this compound. |
Reconstitution and Storage | 2°C to 8°C|-20°C |
Immunogen | Polypeptide |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Mouse |
Concentration | 500 ug/ml |
Specificity | No cross reactivity with other proteins. |
Dilution | Optimal dilutions should be determined by end user. |
Application Info | Western blot: 0.1-0.5 ug/ml: Human, Mouse |
Reference | 1. Morrow, C. S.; Cowan, K. H.; Goldsmith, M. E. : Structure of the human genomic glutathione S-transferase-pi gene. Gene 75: 3-11, 1989 2. Islam, M. Q.; Platz, A.; Szpirer, J.; Szpirer, C.; Levan, G.; Mannervik, B. : Chromosomal localization of human glutathione transferase genes of classes alpha, mu and pi. Hum. Genet. 82: 338-342, 1989. 3. Konohana, A.; Konohana, I.; Schroeder, W. T.; O'Brien, W. R.; Amagai, M.; Greer, J.; Shimizu, N.; Gammon, W. R.; Siciliano, M. J.; Duvic, M. :Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. J. Invest. Derm. 95: 119-126, 1990. |
Storage Buffer | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Description | Rabbit IgG polyclonal antibody for Glutathione S-transferase P(GSTP1) detection. Tested with WB in Human;Mouse. |
Gene Symbol | GSTP1 |
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Gene Full Name | glutathione S-transferase pi 1 |
Alias Symbols | deafness, X-linked 7;DFN7;epididymis secretory protein Li 22;FAEES3;fatty acid ethyl ester synthase III;glutathione S-transferase P;GST class-pi;GST3;GSTP;GSTP1-1;HEL-S-22;PI. |
NCBI Gene Id | 2950 |
Protein Name | Glutathione S-transferase P |
Description of Target | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. |
Uniprot ID | P09211 |
Protein Accession # | NP_000843.1 |
Nucleotide Accession # | NM_000852.3 |
Molecular Weight | 23356 MW |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "GSTP1 Antibody (OABB00137)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Horse|Human|Mouse|Rat".
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How long will it take to receive "GSTP1 Antibody (OABB00137)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "GSTP1 Antibody (OABB00137)" provided in?
This item is provided in "Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "GSTP1 Antibody (OABB00137)"?
This target may also be called "deafness, X-linked 7;DFN7;epididymis secretory protein Li 22;FAEES3;fatty acid ethyl ester synthase III;glutathione S-transferase P;GST class-pi;GST3;GSTP;GSTP1-1;HEL-S-22;PI." in publications.
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What is the shipping cost for "GSTP1 Antibody (OABB00137)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "GSTP1 Antibody (OABB00137)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "GSTP1 Antibody (OABB00137)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "23356 MW".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "GSTP1 Antibody (OABB00137)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "GSTP1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "GSTP1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "GSTP1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "GSTP1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "GSTP1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "GSTP1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.