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Catalog No: OABB00137 (Formerly GWB-BBP061)
Size:100UG
Price: $432.00
SKU
OABB00137
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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Datasheets/ManualsPrintable datasheet for GSTP1 Antibody (OABB00137)
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHorse|Human|Mouse|Rat
Product FormatLyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
ClonalityPolyclonal
ClonePolyclonal
IsotypeRabbit IgG
ApplicationImmunohistochemistry|Western blot
Additional InformationNotes: Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
::Background: Glutathione S-transferases pi, also known as GST3, present in all tissues and cells, with the exception of red cells, in which only erythrocyte GST(GSTe) is observed. The GST-pi gene has 7 exons and 6 introns contained within approximately 2.8 kilobases. The GST-pi gene is mapped to chromosome 11 .Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. GSTP does not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a novel and unexpected role in the toxicity of this compound.
::Background: Glutathione S-transferases pi, also known as GST3, present in all tissues and cells, with the exception of red cells, in which only erythrocyte GST (GSTe) is observed. The GST-pi gene has 7 exons and 6 introns contained within approximately 2.8 kilobases. The GST-pi gene is mapped to chromosome 11 .Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. GSTP does not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a novel and unexpected role in the toxicity of this compound.
Reconstitution and Storage2°C to 8°C|-20°C
ImmunogenPolypeptide
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman; Mouse
Concentration500 ug/ml
SpecificityNo cross reactivity with other proteins.
DilutionOptimal dilutions should be determined by end user.
Application InfoWestern blot: 0.1-0.5 ug/ml: Human, Mouse
Reference1. Morrow, C. S.; Cowan, K. H.; Goldsmith, M. E. : Structure of the human genomic glutathione
S-transferase-pi gene. Gene 75: 3-11, 1989
2. Islam, M. Q.; Platz, A.; Szpirer, J.; Szpirer, C.; Levan, G.; Mannervik, B. : Chromosomal
localization of human glutathione transferase genes of classes alpha, mu and pi. Hum. Genet. 82:
338-342, 1989.
3. Konohana, A.; Konohana, I.; Schroeder, W. T.; O'Brien, W. R.; Amagai, M.; Greer, J.; Shimizu, N.;
Gammon, W. R.; Siciliano, M. J.; Duvic, M. :Placental glutathione-S-transferase-pi mRNA is
abundantly expressed in human skin. J. Invest. Derm. 95: 119-126, 1990.
Storage BufferEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
DescriptionRabbit IgG polyclonal antibody for Glutathione S-transferase P(GSTP1) detection. Tested with WB in Human;Mouse.
Gene SymbolGSTP1
Gene Full Nameglutathione S-transferase pi 1
Alias Symbolsdeafness, X-linked 7;DFN7;epididymis secretory protein Li 22;FAEES3;fatty acid ethyl ester synthase III;glutathione S-transferase P;GST class-pi;GST3;GSTP;GSTP1-1;HEL-S-22;PI.
NCBI Gene Id2950
Protein NameGlutathione S-transferase P
Description of TargetConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
Uniprot IDP09211
Protein Accession #NP_000843.1
Nucleotide Accession #NM_000852.3
Molecular Weight23356 MW
  1. What is the species homology for "GSTP1 Antibody (OABB00137)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Horse|Human|Mouse|Rat".

  2. How long will it take to receive "GSTP1 Antibody (OABB00137)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "GSTP1 Antibody (OABB00137)" provided in?

    This item is provided in "Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GSTP1 Antibody (OABB00137)"?

    This target may also be called "deafness, X-linked 7;DFN7;epididymis secretory protein Li 22;FAEES3;fatty acid ethyl ester synthase III;glutathione S-transferase P;GST class-pi;GST3;GSTP;GSTP1-1;HEL-S-22;PI." in publications.

  5. What is the shipping cost for "GSTP1 Antibody (OABB00137)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GSTP1 Antibody (OABB00137)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GSTP1 Antibody (OABB00137)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "23356 MW".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GSTP1 Antibody (OABB00137)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GSTP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GSTP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GSTP1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GSTP1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GSTP1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GSTP1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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