GSTM5 Antibody (OAGA03289)

Catalog No: OAGA03289

Size:100 ul

Sample (50 ug of whole cell lysate)
A: mouse testis
12% SDS PAGE
diluted at 1:10000

Sample (50 ug of whole cell lysate)
A: rat testis
12% SDS PAGE
diluted at 1:10000

GSTM5 antibody detects GSTM5 protein at cytoplasm in human cervical cancer by immunohistochemical analysis.
Sample: Paraffin-embedded human cervical cancer.
GSTM5 antibody diluted at 1:500.

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using GST Mu5 antibody at 1:200 dilution.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF, IHC-P, WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Full length human GSTM5 Recombinant protein.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:5000-1:20000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: GSTM5
• Gene Full Name: glutathione S-transferase mu 5
• Alias Symbols: GTM5, GSTM5-5
• NCBI Gene Id: 2949
• Protein Name: glutathione S-transferase Mu 5
• Description of Target: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.
• Uniprot ID: P46439
• Protein Accession #: NP_000842.2
• Nucleotide Accession #: NM_000851.3