Size:100 ul
Special Price $229.00 Regular Price $319.00
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ARP53561_P050
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Conjugation Options

ARP53561_P050-FITC Conjugated

ARP53561_P050-HRP Conjugated

ARP53561_P050-Biotin Conjugated

GSTM3 Antibody - middle region (ARP53561_P050)

Rating:
100% of 100
Catalog#: ARP53561_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-133642 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human GSTM3
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 85%; Dog: 77%; Horse: 85%; Human: 100%; Mouse: 79%; Pig: 92%; Rabbit: 86%; Rat: 79%
Complete computational species homology data Anti-GSTM3 (ARP53561_P050)
Peptide Sequence Synthetic peptide located within the following region: EEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMF
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-GSTM3 (ARP53561_P050) antibody is Catalog # AAP53561 (Previous Catalog # AAPS32801)
Datasheets/Manuals Printable datasheet for anti-GSTM3 (ARP53561_P050) antibody
Target Reference Ikeda,S., (2008) Am. J. Gastroenterol. 103 (6), 1476-1487
Gene Symbol GSTM3
Official Gene Full Name Glutathione S-transferase mu 3 (brain)
Alias Symbols GST5, GSTB, GSTM3-3, GTM3, MGC3310, MGC3704
NCBI Gene Id 2947
Protein Name Glutathione S-transferase Mu 3
Description of Target Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM3 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot Id P21266
Protein Accession # NP_000840
Nucleotide Accession # NM_000849
Protein Size (# AA) 225
Molecular Weight 26kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express GSTM3.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express GSTM3.
Protein Interactions GSTM5; GSTM4; GSTM3; GSTM1; UBC; ESR1; BAG3; SUMO2; SH3GL2; UCHL5; GSTM2; MPG;
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