Catalog No: ARP54299_P050
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ARP54299_P050
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GSN Antibody - C-terminal region (ARP54299_P050)

Datasheets/ManualsPrintable datasheet for anti-GSN (ARP54299_P050) antibody
Product Info
ReferenceShokouhi,G. Nephrol. Dial. Transplant. 23 (3), 1071 (2008)
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human GSN
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: KPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN
Concentration0.5 mg/ml
Blocking PeptideFor anti-GSN (ARP54299_P050) antibody is Catalog # AAP54299 (Previous Catalog # AAPP31048)
Gene SymbolGSN
Gene Full NameGelsolin
Alias SymbolsADF, AGEL
NCBI Gene Id2934
Protein NameGelsolin
Description of TargetGSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Uniprot IDP06396
Protein Accession #NP_000168
Nucleotide Accession #NM_000177
Protein Size (# AA)782
Molecular Weight83kDa
Protein InteractionsITCH; CFLAR; TP53; UBC; CASP3; UBD; FN1; MPG; ESR1; ALB; SDHB; ACTA1; MDM2; UBE2Q2; FBXO25; ARRB2; ARRB1; AR; PSMD4; TNIK; CLIC5; TOM1L1; ACTN4; VDAC1; BCAR1; PXN; LIMK2; VASP; PIK3CG; PTK2B; FHIT; VCL; CSK; APP; ACTB; ACTG1; PLCG1; SRC; PTPN12; PTK2; PIK
  1. What is the species homology for "GSN Antibody - C-terminal region (ARP54299_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish".

  2. How long will it take to receive "GSN Antibody - C-terminal region (ARP54299_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "GSN Antibody - C-terminal region (ARP54299_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GSN Antibody - C-terminal region (ARP54299_P050)"?

    This target may also be called "ADF, AGEL" in publications.

  5. What is the shipping cost for "GSN Antibody - C-terminal region (ARP54299_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GSN Antibody - C-terminal region (ARP54299_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GSN Antibody - C-terminal region (ARP54299_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "83kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GSN Antibody - C-terminal region (ARP54299_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GSN"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GSN"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GSN"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GSN"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GSN"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GSN"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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