GSK3B Antibody (Phospho-Ser9) (OAGA08182)

Catalog No: OAGA08182

Size:100 ul

Untreated (–) and treated (+) NIH-3T3 whole cell extracts (18 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with GSK3 alpha (phospho Ser21) + GSK3 beta (phospho Ser9) antibody diluted at 1:1000.

Product Info

• Predicted Species Reactivity: Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Human GSK3 beta (phospho Ser9). The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 0.13 mg/ml
• Preservative: 0.025% ProClin 300
• Target Post-Translational Modification: Phospho-Ser9
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Target Info

• Gene Symbol: GSK3B
• Gene Full Name: glycogen synthase kinase 3 beta
• NCBI Gene Id: 2932
• Protein Name: glycogen synthase kinase-3 beta
• Description of Target: The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
• Uniprot ID: P49841
• Protein Accession #: NP_001139628.1
• Nucleotide Accession #: NM_001146156.1